NCIt definition : The hydrochloride salt form of dronedarone, an orally bioavailable benzofuran derivative,
with anti-arrhythmic activity. Upon oral administration, and although the exact mechanism
of action through which dronedarone exerts its anti-arrhythmic effect has not been
fully elucidated, it inhibits multiple voltage-gated ion channels, including sodium,
potassium, and calcium ion channels, and restores the normal sinus rhythm and reduces
heart rate in atrial fibrillation. It also non-competitively antagonizes adrenergic
receptors.;