Dronedarone - CISMeF

Preferred Label : Dronedarone;

NCIt definition : An orally bioavailable benzofuran derivative, with anti-arrhythmic activity. Upon oral administration, and although the exact mechanism of action through which dronedarone exerts its anti-arrhythmic effect has not been fully elucidated, it inhibits multiple voltage-gated ion channels, including sodium, potassium, and calcium ion channels, and restores the normal sinus rhythm and reduces heart rate in atrial fibrillation. It also non-competitively antagonizes adrenergic receptors.;

UNII : JQZ1L091Y2;

InChIKey : ZQTNQVWKHCQYLQ-UHFFFAOYSA-N;

CAS number : 141626-36-0;

Chemical formula : C31H44N2O5S;

ChEBI ID : CHEBI:50659;

Details

Origin ID

C65485;

UMLS CUI

C0766326;

Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Dronedarone [MeSH Descriptor]
- Dronedarone (substance) [SNOMED CT concept]
- Product containing dronedarone (medicinal product) [SNOMED CT concept]
- dronedarone [ATC Code]
- dronedarone [MeSH concept]
Validated automatic mappings to BTNT
- dronedarone [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Dronedarone Hydrochloride [NCIt concept]
is_free_acid_or_base_form_of
- Dronedarone Hydrochloride [NCIt concept]

Keyword's position in hierarchy(ies) :

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