Doxepin - CISMeF

Preferred Label : Doxepin;

NCIt definition : A dibenzoxepin derivative and tricyclic antidepressant (TCA) with antipruritic, antidepressive and anxiolytic activities. Doxepin blocks the reuptake of norepinephrine and serotonin (5-HT) into presynaptic terminals thereby prolonging the availability of the monoaminergic neurotransmitters within the synaptic cleft and enhancing their neurotransmission. Doxepin also has antagonistic effects on histamine H1, 5-HT2, alpha-1 adrenergic, and muscarinic receptors. The antipruritic effect of this agent is mediated through inhibition of histamine receptors.;

UNII : 5ASJ6HUZ7D;

CAS number : 1668-19-5;

Drug name : Silenor;

ChEBI ID : CHEBI:4710;

Details

Origin ID

C65475;

UMLS CUI

C0013085;

Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Doxepin [LOINC component]
- Doxepin (substance) [SNOMED CT concept]
- Product containing doxepin (medicinal product) [SNOMED CT concept]
- doxepin [ATC Code]
- doxepin [Substance BNPC]
- doxepin [ATC Code]
- doxepin [MeSH concept]
- doxepin [MeSH Descriptor]
- doxepin [SNOMED Notion]
Validated automatic mappings to BTNT
- doxepin [ATC Code]
- doxepin [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Doxepin Hydrochloride [NCIt concept]
is_free_acid_or_base_form_of
- Doxepin Hydrochloride [NCIt concept]

Keyword's position in hierarchy(ies) :

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