Dofequidar - CISMeF

Preferred Label : Dofequidar;

NCIt synonyms : 5-[3-[4-(2,2-Diphenylacetyl)piperazin-1-yl]-2-hydroxypropoxy]quinoline;

NCIt definition : An orally-available synthetic quinoline derivative with multidrug resistance modulating properties. Dofequidar binds to the drug-binding site of the transmembrane P-glycoprotein efflux pump and is preferentially transported from the cell, thereby blocking the efflux of other therapeutic agents.;

UNII : 0BJK6B565B;

InChIKey : KLWUUPVJTLHYIM-UHFFFAOYSA-N;

CAS number : 129716-58-1;

Chemical formula : C30H31N3O3;

Details

Origin ID

C65458;

UMLS CUI

C1698867;

Currated CISMeF NLP mapping
- dofequidar [MeSH concept]
- dofequidar [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- dofequidar [MeSH concept]
- dofequidar [MeSH Supplementary Concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Dofequidar Fumarate [NCIt concept]
is_free_acid_or_base_form_of
- Dofequidar Fumarate [NCIt concept]

Keyword's position in hierarchy(ies) :

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