Carbenicillin Disodium

Preferred Label : Carbenicillin Disodium;

NCIt definition : The disodium salt form of carbenicillin, a broad-spectrum, semi-synthetic penicillin antibiotic with bactericidal and beta-lactamase resistant activity. Carbenicillin acylates the penicillin-sensitive transpeptidase C-terminal domain by opening the lactam ring. This inactivation prevents the cross-linkage of peptidoglycan strands, thereby inhibiting the third and last stage of bacterial cell wall synthesis. This leads to incomplete bacterial cell wall synthesis and eventually causes cell lysis.;

UNII : 9TS4B3H261;

InChIKey : RTYJTGSCYUUYAL-YCAHSCEMSA-L;

CAS number : 4800-94-6;

Chemical formula : C17H16N2O6S.2Na;

NSC code : 111071;

ChEBI ID : CHEBI:34609;

Details

Origin ID

C65285;

UMLS CUI

C0813202;

Automatic exact mappings (from CISMeF team)
- carbenicillin [MeSH Descriptor]
Currated CISMeF NLP mapping
- CARBENICILLIN SODIUM [SMS substance]
- Carbenicillin Disodium [MeSH concept]
- Carbenicillin disodium (substance) [SNOMED CT concept]
- carbenicillin disodium [SNOMED Notion]
Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Carbenicillin Disodium [MeSH concept]
- Carbenicillin disodium (substance) [SNOMED CT concept]
- carbenicillin disodium [SNOMED Notion]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_free_acid_or_base_form
- Carbenicillin [NCIt concept]
is_salt_form_of
- Carbenicillin [NCIt concept]

Keyword's position in hierarchy(ies) :

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