Carbenicillin - CISMeF

Preferred Label : Carbenicillin;

NCIt related terms : Pyopen; Geopen;

NCIt definition : A broad-spectrum, semi-synthetic penicillin antibiotic with bactericidal and beta-lactamase resistant activity. Carbenicillin acylates the penicillin-sensitive transpeptidase C-terminal domain by opening the lactam ring. This inactivation prevents the cross-linkage of peptidoglycan strands, thereby inhibiting the third and last stage of bacterial cell wall synthesis. This leads to incomplete bacterial cell wall synthesis and eventually causes cell lysis.;

UNII : G42ZU72N5G;

InChIKey : FPPNZSSZRUTDAP-UWFZAAFLSA-N;

CAS number : 4697-36-3;

Drug name : Pyopen; Geopen;

Chemical formula : C17H18N2O6S;

ChEBI ID : CHEBI:3393;

Codes from synonyms : NSC0111071;

Details

Origin ID

C343;

UMLS CUI

C0006976;

Currated CISMeF NLP mapping
- Carbenicillin [ICD-11 Extension code]
- Carbenicillin [ICHI extension code]
- Carbenicillin [SMS substance]
- Carbenicillin [LOINC component]
- Carbenicillin (substance) [SNOMED CT concept]
- Product containing carbenicillin (medicinal product) [SNOMED CT concept]
- carbenicillin [Substance BNPC]
- carbenicillin [MeSH Descriptor]
- carbenicillin [MeSH concept]
- carbenicillin [SNOMED Notion]
Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Carbenicillin [ICD-11 Extension code]
- Carbenicillin [LOINC component]
- Carbenicillin (substance) [SNOMED CT concept]
- Product containing carbenicillin (medicinal product) [SNOMED CT concept]
- carbenicillin [ATC Code]
- carbenicillin [Substance BNPC]
- carbenicillin [MeSH concept]
- carbenicillin [MeSH Descriptor]
- carbenicillin [SNOMED Notion]
Validated automatic mappings to BTNT
- carbenicillin [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_salt_form
- Carbenicillin Disodium [NCIt concept]
is_free_acid_or_base_form_of
- Carbenicillin Disodium [NCIt concept]

Keyword's position in hierarchy(ies) :

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