" /> Bitolterol Mesylate - CISMeF





Preferred Label : Bitolterol Mesylate;

NCIt synonyms : Alpha-[tert-butylaminomethyl]-3,4- dihydroxybenzyl alcohol 3,4-di(p-toluate) Methanesulfonate;

NCIt definition : The mesylate salt of bitolterol, a diester sympathomimetic amine with bronchodilator activity. As an ester prodrug, bitolterol is hydrolyzed by esterases to its active metabolite colterol (N-t-butylarterenol). Colterol selectively binds to and activates beta-2 adrenergic receptors in bronchiolar smooth muscle, thereby causing stimulation of adenyl cyclase, the enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3',5'-adenosine monophosphate (cAMP). Increased intracellular cAMP levels cause relaxation of bronchial smooth muscle. This increases air flow and prevents bronchospasms and may eventually lead to an improvement of airway function.;

UNII : 4E53T3611U;

InChIKey : HODFCFXCOMKRCG-UHFFFAOYSA-N;

CAS number : 30392-41-7;

Molecule name : WIN 37284;

Chemical formula : C28H31NO5.CH4O3S;

ChEBI ID : CHEBI:3134;

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08/05/2025


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