Bitolterol - CISMeF

Preferred Label : Bitolterol;

NCIt definition : A diester sympathomimetic amine with bronchodilator activity. As an ester prodrug, bitolterol is hydrolyzed by esterases to its active metabolite colterol (N-t-butylarterenol). Colterol selectively binds to and activates beta-2 adrenergic receptors in bronchiolar smooth muscle, thereby causing stimulation of adenyl cyclase, the enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3',5'-adenosine monophosphate (cAMP). Increased intracellular cAMP levels cause relaxation of bronchial smooth muscle. This increases air flow and prevents bronchospasms and may eventually lead to an improvement of airway function.;

UNII : 9KY0QXD6LI;

InChIKey : FZGVEKPRDOIXJY-UHFFFAOYSA-N;

CAS number : 30392-40-6;

Chemical formula : C28H31NO5;

ChEBI ID : CHEBI:3133;

Détails

Origin ID

C65267;

UMLS CUI

C0053817;

Automatic exact mappings (from CISMeF team)
- Bitolterol [ICHI extension code]
Currated CISMeF NLP mapping
- Bitolterol [ICD-11 Extension code]
- Bitolterol (substance) [SNOMED CT concept]
- Product containing bitolterol (medicinal product) [SNOMED CT concept]
- bitolterol [MeSH concept]
- bitolterol [MeSH Supplementary Concept]
- bitolterol [SNOMED Notion]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Bitolterol [ICD-11 Extension code]
- Bitolterol (substance) [SNOMED CT concept]
- Product containing bitolterol (medicinal product) [SNOMED CT concept]
- bitolterol [ATC Code]
- bitolterol [SNOMED Notion]
- bitolterol [MeSH concept]
- bitolterol [MeSH Supplementary Concept]
Validated automatic mappings to BTNT
- bitolterol [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Bitolterol Mesylate [NCIt concept]
is_free_acid_or_base_form_of
- Bitolterol Mesylate [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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