Bacampicillin - CISMeF

Preferred Label : Bacampicillin;

NCIt definition : A prodrug of ampicillin, a broad-spectrum, semisynthetic, beta-lactam aminopenicillin antibiotic with bactericidal activity. Bacampicillin is hydrolyzed in vivo by esterases to its active metabolite ampicillin. Ampicillin binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall and causes cell lysis.;

UNII : 8GM2J22278;

InChIKey : PFOLLRNADZZWEX-FFGRCDKISA-N;

CAS number : 50972-17-3;

Chemical formula : C21H27N3O7S;

ChEBI ID : CHEBI:2968;

Details

Origin ID

C65245;

UMLS CUI

C0052865;

Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Bacampicillin [ICD-11 Extension code]
- Bacampicillin [LOINC component]
- Bacampicillin (substance) [SNOMED CT concept]
- Product containing bacampicillin (medicinal product) [SNOMED CT concept]
- bacampicillin [ATC Code]
- bacampicillin [MeSH concept]
- bacampicillin [SNOMED Notion]
- bacampicillin [MeSH Supplementary Concept]
Validated automatic mappings to BTNT
- bacampicillin [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Bacampicillin Hydrochloride [NCIt concept]
is_free_acid_or_base_form_of
- Bacampicillin Hydrochloride [NCIt concept]

Keyword's position in hierarchy(ies) :

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