Metronidazole - CISMeF

Preferred Label : Metronidazole;

NCIt related terms : Flagyl; Tricom;

NCIt definition : A synthetic nitroimidazole derivative with antiprotozoal and antibacterial activities. Although its mechanism of action is not fully elucidated, un-ionized metronidazole is readily taken up by obligate anaerobic organisms and is subsequently reduced by low-redox potential electron-transport proteins to an active, intermediate product. Reduced metronidazole causes DNA strand breaks, thereby inhibiting DNA synthesis and bacterial cell growth.;

Alternative definition : NCI-GLOSS: A drug that is used to treat infection and is being studied in the treatment of cancer. It is a type of antibacterial, antiprotozoal, and anthelmintic.;

UNII : 140QMO216E;

InChIKey : VAOCPAMSLUNLGC-UHFFFAOYSA-N;

CAS number : 443-48-1;

Drug name : Flagyl I.V. RTU;

Chemical formula : C6H9N3O3;

NSC code : 50364; 69587;

ChEBI ID : CHEBI:6909;

Codes from synonyms : NSC0069587; CDR0000413945; CDR0000045226; 26852;

Details

Origin ID

C651;

UMLS CUI

C0025872;

Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Metronidazole [ICD-11 Extension code]
- Metronidazole (substance) [SNOMED CT concept]
- Product containing metronidazole (medicinal product) [SNOMED CT concept]
- metroNIDAZOLE [LOINC component]
- metronidazole [ATC Code]
- metronidazole [ATC Code]
- metronidazole [ATC Code]
- metronidazole [ATC Code]
- metronidazole [ATC Code]
- metronidazole [Substance BNPC]
- metronidazole [MeSH concept]
- metronidazole [MeSH Descriptor]
- metronidazole [SNOMED Notion]
Validated automatic mappings to BTNT
- Flagyl [ICD-11 Extension code]
- metronidazole [ATC Code]
- metronidazole [ATC Code]
- metronidazole [ATC Code]
- metronidazole [ATC Code]
- metronidazole [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- HemOnc Agent Terminology [NCIt concept]
has_salt_form
- Metronidazole Hydrochloride [NCIt concept]
is_component_of_chemotherapy_regimen
- Bismuth Subcitrate/Metronidazole/Omeprazole/Tetracycline [NCIt concept]
- Cyclosporine/Dipyridamole/Etoposide/Ketoconazole/Metronidazole/Quinidine/Tamoxifen [NCIt concept]
- Dipyridamole/Etoposide/Ketoconazole/Metronidazole [NCIt concept]
- Dipyridamole/Etoposide/Ketoconazole/Metronidazole/Quinidine/Tamoxifen [NCIt concept]
- Dipyridamole/Etoposide/Ketoconazole/Metronidazole/Tamoxifen [NCIt concept]
- Etoposide/Ketoconazole/Metronidazole [NCIt concept]
- Etoposide/Metronidazole [NCIt concept]
is_free_acid_or_base_form_of
- Metronidazole Hydrochloride [NCIt concept]

Keyword's position in hierarchy(ies) :

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