" /> EGFR/HER2 Inhibitor AV-412 - CISMeF





Preferred Label : EGFR/HER2 Inhibitor AV-412;

NCIt related terms : AV-412;

NCIt definition : A second-generation, orally bioavailable dual kinase inhibitor with potential antineoplastic activity. EGFR/HER2 inhibitor AV-412 binds to and inhibits the epidermal growth factor receptor (EGFR) and the human epidermal growth factor receptor 2 (HER2), which may result in the inhibition of tumor growth and angiogenesis, and tumor regression in EGFR/HER2-expressing tumors. This agent may be active against EGFR/HER2-expressing tumor cells that are resistant to first-generation kinase inhibitors. EGFR and HER2 are receptor tyrosine kinases that play major roles in tumor cell proliferation and tumor vascularization.;

UNII : Z541VW0W40;

InChIKey : GTWJVFFZCKODEV-UHFFFAOYSA-N;

CAS number : 451493-31-5; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 451493-31-5 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : MP-412; AV-412; MP 412; AV 412;

Details


Keyword's position in hierarchy(ies) : arborescence

You can consult :


Nous contacter.
14/05/2024


[Home] [Top]

© Rouen University Hospital. Any partial or total use of this material must mention the source.