Cenisertib - CISMeF

Preferred Label : Cenisertib;

NCIt synonyms : Aurora Kinase Inhibitor AS703569;

NCIt definition : A water-soluble, synthetic small molecule with potential antineoplastic activity. Cenisertib selectively binds to and inhibits aurora kinases (AKs), a family of serine-threonine kinases which are important regulators of cell division and proliferation, and which are overexpressed in certain types of cancer. Inhibition of aurora kinases inhibits cell division and proliferation and induces apoptosis in tumor cells overexpressing AKs.;

UNII : 5277GPA358;

InChIKey : KSOVGRCOLZZTPF-QMKUDKLTSA-N;

CAS number : 871357-89-0;

Molecule name : AS703569; R763;

Chemical formula : C24H30FN7O;

Détails

Origin ID

C64540;

UMLS CUI

C3266920;

Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
chemical_or_drug_affects_gene_product
- Aurora Kinase A [NCIt concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- Aurora Kinase A [NCIt concept]
- Aurora Kinase B [NCIt concept]
- Aurora Kinase C [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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