Methoxsalen - CISMeF

Preferred Label : Methoxsalen;

NCIt synonyms : 9-Methoxy-7H-furo[3,2-g][1]benzopyran-7-one; 8-Methoxypsoralen; Methoxypsoralen;

NCIt related terms : Oxsoralen; XANTHOTOXIN; Ammoidin; Meladinine; 8-MOP;

NCIt definition : A naturally occurring substance isolated from the seeds of the plant Ammi majus with photoactivating properties. As a member of the family of compounds known as psoralens or furocoumarins, methoxsalen's exact mechanism of action is unknown; upon photoactivation, methoxsalen has been observed to bind covalently to and crosslink DNA. (NCI04);

Alternative definition : NCI-GLOSS: A drug used together with UV light to treat psoriasis, vitiligo, and skin nodules of cutaneous T-cell lymphoma. It is also being studied in the treatment of graft-versus-host disease. It belongs to the family of drugs called psoralens and furocoumarins.;

UNII : U4VJ29L7BQ;

InChIKey : QXKHYNVANLEOEG-UHFFFAOYSA-N;

CAS number : 298-81-7;

Drug name : Metoxaleno; Ultramop; Ammoidin; Uvadex; Meladinina; Oxsoralen; Meladinine; Xanthotoxin; Mopsoralen; Deltasoralen; Geralen; Oxsoralen-Ultra; Geroxalen; Dermox; Puvasoralen;

Chemical formula : C12H8O4;

NSC code : 45923;

ChEBI ID : CHEBI:18358;

Codes from synonyms : 00200; NSC0045923; CDR0000045224; 330;

Details

Origin ID

C643;

UMLS CUI

C0025684;

Automatic exact mappings (from CISMeF team)
- Xanthotoxin [ICHI extension code]
See also inter- (CISMeF)
- Product containing methoxsalen (medicinal product) [SNOMED CT concept]
- Xanthotoxin [ICD-11 Extension code]
Semantic type(s)
- Biologically Active Substance [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- 8-Methoxypsoralen (8-MOP) [ICD-11 Extension code]
- 9-methoxyfuro[3,2-g]chromen-7-one [Substance BNPC]
- Methoxsalen [ICD-11 Extension code]
- Methoxsalen [LOINC component]
- Methoxsalen (substance) [SNOMED CT concept]
- Product containing methoxsalen (medicinal product) [SNOMED CT concept]
- methoxsalen [ATC Code]
- methoxsalen [ATC Code]
- methoxsalen [International Nonproprietary Name]
- methoxsalen [MeSH Descriptor]
- methoxsalen [MeSH concept]
- methoxsalen [SNOMED Notion]
Validated automatic mappings to BTNT
- methoxsalen [ATC Code]
- methoxsalen [ATC Code]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- HemOnc Agent Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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