Methimazole - CISMeF

Preferred Label : Methimazole;

NCIt related terms : Tapazole;

NCIt definition : A thioamide inhibitor of the enzyme thyroid peroxidase (TPO), with antithyroid activity. Upon administration, methimazole inhibits the metabolism of iodide and the iodination of tyrosine residues in the thyroid hormone precursor thyroglobulin by TPO; this prevents the synthesis of the thyroid hormones triiodothyronine (T3) and thyroxine (T4).;

UNII : 554Z48XN5E;

InChIKey : PMRYVIKBURPHAH-UHFFFAOYSA-N;

CAS number : 60-56-0;

Drug name : Tapazole;

Chemical formula : C4H6N2S;

NSC code : 38608;

ChEBI ID : CHEBI:50673;

Codes from synonyms : NSC0038608;

Details

Origin ID

C641;

UMLS CUI

C0025644;

See also inter- (CISMeF)
- Product containing thiamazole (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Methimazole [ICD-11 Extension code]
- Product containing thiamazole (medicinal product) [SNOMED CT concept]
- Thiamazole (substance) [SNOMED CT concept]
- methIMAzole [LOINC component]
- methimazole [International Nonproprietary Name]
- methimazole [MeSH Descriptor]
- methimazole [MeSH concept]
- methimazole preparation [SNOMED Notion]
- thiamazole [ATC Code]
- thiamazole [Substance BNPC]
Validated automatic mappings to BTNT
- thiamazole [ATC Code]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_target
- Thyroid Peroxidase [NCIt concept]

Keyword's position in hierarchy(ies) :

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