Preferred Label : Glucuronic Acid;
NCIt definition : A carboxylic acid with structural similarity to glucose with detoxifying activity.
The xenobiotic metabolism of various substances such as drugs, pollutants, bilirubin,
androgens, estrogens, mineralocorticoids, glucocorticoids, fatty acid derivatives,
retinoids, and bile acids involves glucuronidation, a process in which water-soluble,
excretable glucuronides of these substances are formed via glycosidic linkages to
glucuronic acid. UDP-glucuronic acid, formed in the liver through the linkage of glucuronic
acid to uridine diphosphate (UDP) via a glycosidic bond, is an intermediate in the
process of glucuronidation.;
Alternative definition : NCI-GLOSS: A form of a type of sugar called glucose that helps remove harmful substances
from the body. Glucuronic acid and the harmful substance combine in the liver and
then are passed in the urine. Glucuronic acid is also found in other substances in
the body, such as cartilage and synovial fluid (fluid found in the joints).;
UNII : 8A5D83Q4RW;
InChIKey : IAJILQKETJEXLJ-QTBDOELSSA-N;
CAS number : 6556-12-3;
Chemical formula : C6H10O7;
ChEBI ID : CHEBI:4178; CHEBI:47953;
Codes from synonyms : CDR0000648598;
Origin ID : C63810;
UMLS CUI : C0061444;
Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- Semantic type(s)
- concept_is_in_subset
