" /> Melphalan - CISMeF





Preferred Label : Melphalan;

NCIt synonyms : L-Sarcolysine; 4-[bis(2-chloroethyl)amino]-L-phenylalanine; Phenylalanine Mustard; L-Sarcolysin Phenylalanine mustard; p-di(chloroethyl)amino-L-phenylalanine; Phenylalanine Nitrogen Mustard; L-PAM; Sarcoclorin;

NCIt related terms : Alanine Nitrogen Mustard; L-Phenylalanine mustard; L-Sarcolysin; Sarkolysin;

NCIt definition : A phenylalanine derivative of nitrogen mustard with antineoplastic activity. Melphalan alkylates DNA at the N7 position of guanine and induces DNA inter-strand cross-linkages, resulting in the inhibition of DNA and RNA synthesis and cytotoxicity against both dividing and non-dividing tumor cells.;

Alternative definition : NCI-GLOSS: A drug that is used to treat multiple myeloma and ovarian epithelial cancer and is being studied in the treatment of other types of cancer. It belongs to the family of drugs called alkylating agents.;

UNII : Q41OR9510P;

InChIKey : SGDBTWWWUNNDEQ-LBPRGKRZSA-N;

CAS number : 148-82-3; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 148-82-3 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Sarkolysin; Melphalanum;

Molecule name : CB-3025; WR-19813;

Chemical formula : C13H18Cl2N2O2;

NSC code : 8806; 241286;

ChEBI ID : CHEBI:28876;

Codes from synonyms : NSC0241286; CDR0000045957; NSC0008806; 325;

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15/05/2024


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