HLA Class I Histocompatibility Antigen, A-1 Alpha Chain

Preferred Label : HLA Class I Histocompatibility Antigen, A-1 Alpha Chain;

NCIt synonyms : HLA-A1 Antigen; MHC Class I Antigen A*1; HLA-A*1; HLA-A1; HLA-A*01;

NCIt definition : HLA class I histocompatibility antigen, A-1 alpha chain protein (365 aa, 41 kDa) is encoded by the HLA-A gene. This protein plays a role in the presentation of foreign antigens to the immune system. It is associated with a number of diseases including graft-versus-host disease, hemochromatosis and certain types of cancer.;

Details

Origin ID

C62772;

UMLS CUI

C1881019;

Currated CISMeF NLP mapping
- HLA-A1 antigen [MeSH Descriptor]
- HLA-A1 antigen [MeSH concept]
- Human leukocyte antigen A1 (substance) [SNOMED CT concept]
- hla-a1 antigen [SNOMED Notion]
OMIM relation
- Major histocompatibility complex, class i, a [OMIM Phenotype]
See also inter- (CISMeF)
- HLA class I histocompatibility antigen, A-1 alpha chain [MeSH concept]
- HLA-A1 [LOINC component]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- HLA class I histocompatibility antigen, A-1 alpha chain [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- HLA-A Gene [NCIt concept]
- Immunoprotein Gene [NCIt concept]
- MHC Class I Gene [NCIt concept]
gene_product_expressed_in_tissue
- CD8-Positive T-Lymphocyte [NCIt concept]
gene_product_has_chemical_classification
- HLA Complex [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- Transmembrane Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Antigen Presentation [NCIt concept]
- Immune Response Process [NCIt concept]
- Immune System Process [NCIt concept]
- Immunoregulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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