Preferred Label : Folate-FITC;
NCIt synonyms : Folate Fluorescein Isothiocyanate Conjugate; EC17; L-glutamine, N2-(4-(((2-amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-n-(2-((((3',6'-dihydroxy-3-oxospiro(isobenzofuran-1(3h),9'-(9h)xanthen)-5-yl)amino)thioxomethyl)amino)ethyl)-;
NCIt related terms : EC-17;
NCIt definition : A conjugate consisting of fluorescein isothiocyanate (FITC) conjugated with folate
with potential antineoplastic activity. Folate-FITC binds to folate receptors, which
are overexpressed on the surfaces of many cancer cells including kidney and ovarian
cancer cells. Once bound to the cancer cell through the folate moiety of the conjugate,
circulating anti-fluorescein antibodies may recognize and bind to the FITC moiety,
resulting in antibody-dependent cellular cytotoxicity.;
UNII : V7YQ6134AE;
InChIKey : ZMTAPBHUSYTHBY-PMERELPUSA-N;
CAS number : 583037-91-6; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 583037-91-6
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G-SRS /a ;
Molecule name : EC-17;
Origin ID : C62479;
UMLS CUI : C1831885;
Semantic type(s)
- concept_is_in_subset
- has_target
