NY-ESO-1 Plasmid DNA Cancer Vaccine pPJV7611 - CISMeF
NY-ESO-1 Plasmid DNA Cancer Vaccine pPJV7611NCIt concept
Preferred Label : NY-ESO-1 Plasmid DNA Cancer Vaccine pPJV7611;
NCIt synonyms : pPJV7611 Vaccine; NY-ESO-1 Plasmid DNA Vaccine;
NCIt definition : A plasmid DNA encoding an immunogenic peptide derived from the cancer-testis antigen
NY-ESO-1 with potential immunostimulating and antitumor activities. Upon administration,
NY-ESO-1 plasmid DNA cancer vaccine pPJV7611 may stimulate the host immune system
to mount a cytotoxic T lymphocyte (CTL) response against tumor cells expressing the
NY-ESO-1 antigen, resulting in tumor cell lysis. NY-ESO-1 is a tumor associated antigen
(TAA) found in normal testes and expressed on the surfaces of various tumor cells,
including melanoma, breast, bladder, prostate, lung, ovarian, and hepatocellular tumor
cells.;