Recombinant Tumor Necrosis Factor-Beta

Preferred Label : Recombinant Tumor Necrosis Factor-Beta;

NCIt synonyms : TNF beta; Lymphotoxin-Alpha; Tumor Necrosis Factor-Beta; Lymphotoxin A; Therapeutic Tumor Necrosis Factor-Beta;

NCIt related terms : Lymphotoxin;

NCIt definition : A recombinant agent, which is chemically identical to or similar to the endogenous cytokine tumor necrosis factor-beta (TNF-beta). Produced predominantly by T-lymphocytes and leukocytes, TNF-beta is cytolytic or cytostatic for many tumor cells, and can inhibit the growth of endothelial cells, resulting in an antiangiogenic effect. (NCI04);

Codes from synonyms : 30812;

Details

Origin ID

C622;

UMLS CUI

C1527150;

Currated CISMeF NLP mapping
- Tumor necrosis factor beta (substance) [SNOMED CT concept]
- lymphotoxin [SNOMED Notion]
- tumor necrosis factor beta [SNOMED Notion]
False automatic mappings
- lymphotoxin-alpha [MeSH Descriptor]
- lymphotoxin-alpha [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
is_related_to_endogenous_product
- Lymphotoxin-Alpha [NCIt concept]

Keyword's position in hierarchy(ies) :

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