Tolterodine - CISMeF

Preferred Label : Tolterodine;

NCIt synonyms : Tolterodine Base;

NCIt definition : A benzhydryl compound and a muscarinic receptor antagonist possessing both antimuscarinic and antispasmodic properties. Both tolterodine and its active metabolite, 5-hydroxymethyltolterodine, competitively blocks muscarinic receptors, thereby inhibiting acetylcholine binding. This antagonistic action results in an increase in residual urine, reflecting an incomplete emptying of the bladder, and a decrease in detrusor pressure, indicating an antimuscarinic action on the lower urinary tract. The 5-hydroxymethyl metabolite appears to contribute significantly to the therapeutic effects.;

UNII : WHE7A56U7K;

InChIKey : OOGJQPCLVADCPB-HXUWFJFHSA-N;

CAS number : 124937-51-5;

Chemical formula : C22H31NO;

ChEBI ID : CHEBI:9622;

Details

Origin ID

C62083;

UMLS CUI

C0388753;

Currated CISMeF NLP mapping
- Product containing tolterodine (medicinal product) [SNOMED CT concept]
- Tolterodine [LOINC component]
- Tolterodine [ICD-11 Extension code]
- Tolterodine [SMS substance]
- Tolterodine (substance) [SNOMED CT concept]
- Tolterodine Tartrate [MeSH Descriptor]
- tolterodine [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing tolterodine (medicinal product) [SNOMED CT concept]
- Tolterodine [LOINC component]
- Tolterodine (substance) [SNOMED CT concept]
- tolterodine [ATC Code]
- tolterodine [MeSH concept]
Validated automatic mappings to BTNT
- Tolterodine tartrate [SMS substance]
- tolterodine [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Tolterodine Tartrate [NCIt concept]
is_free_acid_or_base_form_of
- Tolterodine Tartrate [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients