Tolterodine Tartrate

Preferred Label : Tolterodine Tartrate;

NCIt synonyms : Tolterodine;

NCIt definition : The tartrate salt form of tolterodine, a benzhydryl compound and a muscarinic receptor antagonist possessing both antimuscarinic and antispasmodic properties. Both tolterodine and its active metabolite, 5-hydroxymethyltolterodine, competitively blocks muscarinic receptors, thereby inhibiting acetylcholine receptor binding. This antagonistic action results in an increase in residual urine, reflecting an incomplete emptying of the bladder, and a decrease in detrusor pressure, indicating an antimuscarinic action on the lower urinary tract.. The 5-hydroxymethyl metabolite appears to contribute significantly to the therapeutic effects.;

UNII : 5T619TQR3R;

CAS number : 124937-52-6;

Drug name : Detrusitol; Detrol;

Chemical formula : C22H31NO.C4H6O6;

ChEBI ID : CHEBI:32245;

Details

Origin ID

C29504;

UMLS CUI

C0724710;

CISMeF manual mappings
- Tolterodine Tartrate [MeSH Descriptor]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Tolterodine Tartrate [MeSH Descriptor]
- Tolterodine tartrate (product) [Inactive SNOMED CT concept]
- Tolterodine tartrate (substance) [SNOMED CT concept]
- tolterodine tartrate [MeSH concept]
Validated automatic mappings to BTNT
- tolterodine [ATC Code]
Validated automatic mappings to NTBT
- Tolterodine [LOINC component]
- Tolterodine [SMS substance]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_free_acid_or_base_form
- Tolterodine [NCIt concept]
is_salt_form_of
- Tolterodine [NCIt concept]

Keyword's position in hierarchy(ies) :

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