" /> Phentolamine - CISMeF





Preferred Label : Phentolamine;

NCIt synonyms : 2-[N-p'-Tolyl-N-(m'-hydroxyphenyl)aminomethyl]imidazoline; Phentolamine Base;

NCIt definition : A synthetic imidazoline with alpha-adrenergic antagonist activity. As a competitive alpha-adrenergic antagonist, phentolamine binds to alpha-1 and alpha-2 receptors, resulting in a decrease in peripheral vascular resistance and vasodilatation. This agent also may block 5-hydroxytryptamine (5-HT) receptors and stimulate release of histamine from mast cells.;

UNII : Z468598HBV;

InChIKey : MRBDMNSDAVCSSF-UHFFFAOYSA-N;

CAS number : 50-60-2;

Chemical formula : C17H19N3O;

Codes from synonyms : 04041;

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08/05/2025


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