Phentolamine Mesylate

Preferred Label : Phentolamine Mesylate;

NCIt synonyms : 2-[N-p'-Tolyl-N-(m'-hydroxyphenyl)aminomethyl]imidazoline Monomethanesulfonate; Phentolamine;

NCIt definition : The mesylate salt of a synthetic imidazoline with alpha-adrenergic antagonist activity. As a competitive alpha-adrenergic antagonist, phentolamine binds to alpha-1 and alpha-2 receptors, resulting in a decrease in peripheral vascular resistance and vasodilatation. This agent also may block 5-hydroxytryptamine (5-HT) receptors and stimulate release of histamine from mast cells.;

UNII : Y7543E5K9T;

InChIKey : OGIYDFVHFQEFKQ-UHFFFAOYSA-N;

CAS number : 65-28-1;

Drug name : Regitine;

Chemical formula : C17H19N3O.CH4O3S;

Details

Origin ID

C38691;

UMLS CUI

C0733398;

Automatic exact mappings (from CISMeF team)
- Phentolamine [ICHI extension code]
- Product containing phentolamine (medicinal product) [SNOMED CT concept]
- phentolamine [ATC Code]
- phentolamine [ATC Code]
CISMeF manual mappings
- phentolamine mesylate [International Nonproprietary Name]
See also inter- (CISMeF)
- Phentolamine mesylate product (product) [Inactive SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
Validated automatic mappings to NTBT
- Phentolamine [ICD-11 Extension code]
- Phentolamine [SMS substance]
- Phentolamine (substance) [SNOMED CT concept]
- phentolamine [SNOMED Notion]
- phentolamine [Substance BNPC]
- phentolamine [MeSH concept]
- phentolamine [MeSH Descriptor]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_free_acid_or_base_form
- Phentolamine [NCIt concept]
is_salt_form_of
- Phentolamine [NCIt concept]

Keyword's position in hierarchy(ies) :

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