Phenoxybenzamine

Preferred Label : Phenoxybenzamine;

NCIt synonyms : N-(2-chloroethyl)-N-(1-methyl-2-phenoxyethyl)-benzenemethanamine; Phenoxybenzamine Base;

NCIt definition : A synthetic, dibenzamine alpha adrenergic antagonist with antihypertensive and vasodilatory properties. Phenoxybenzamine non-selectively and irreversibly blocks the postsynaptic alpha-adrenergic receptor in smooth muscle, thereby preventing vasoconstriction, relieving vasospasms, and decreasing peripheral resistance. Reflex tachycardia may occur and may be enhanced by blockade of alpha-2 receptors which enhances norepinephrine release. Phenoxybenzamine is reasonably anticipated to be a human carcinogen.;

UNII : 0TTZ664R7Z;

InChIKey : QZVCTJOXCFMACW-UHFFFAOYSA-N;

CAS number : 59-96-1;

Chemical formula : C18H22ClNO;

Details

Origin ID

C62065;

UMLS CUI

C0031441;

Automatic exact mappings (from CISMeF team)
- Phenoxybenzamine [ICHI extension code]
See also inter- (CISMeF)
- Product containing phenoxybenzamine (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Phenoxybenzamine [ICD-11 Extension code]
- Phenoxybenzamine (substance) [SNOMED CT concept]
- Product containing phenoxybenzamine (medicinal product) [SNOMED CT concept]
- phenoxybenzamine [ATC Code]
- phenoxybenzamine [Substance BNPC]
- phenoxybenzamine [MeSH Descriptor]
- phenoxybenzamine [SNOMED Notion]
- phenoxybenzamine [MeSH concept]
Validated automatic mappings to BTNT
- phenoxybenzamine [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Phenoxybenzamine Hydrochloride [NCIt concept]
is_free_acid_or_base_form_of
- Phenoxybenzamine Hydrochloride [NCIt concept]

Keyword's position in hierarchy(ies) :

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