Hydralazine - CISMeF

Preferred Label : Hydralazine;

NCIt synonyms : 1(2H)-Phthalazinone Hydrazone; Hydralazine Base;

NCIt definition : A phthalazine derivative with antihypertensive effects. Hydralazine exerts its vasodilatory effects through modification of the contractile state of arterial vascular smooth muscle by altering intracellular calcium release, and interfering with smooth muscle cell calcium influx. This agent also causes inhibition of phosphorylation of myosin protein or chelation of trace metals required for smooth muscle contraction, thereby resulting in an increase in heart rate, stroke volume and cardiac output.;

UNII : 26NAK24LS8;

InChIKey : RPTUSVTUFVMDQK-UHFFFAOYSA-N;

CAS number : 86-54-4;

Chemical formula : C8H8N4;

NSC code : 126699;

ChEBI ID : CHEBI:5775;

Codes from synonyms : NSC0126699; 02098;

Details

Origin ID

C62032;

UMLS CUI

C0020223;

Automatic exact mappings (from CISMeF team)
- Hydralazine [ICHI extension code]
See also inter- (CISMeF)
- Product containing hydralazine (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Hydralazine [ICD-11 Extension code]
- Hydralazine (substance) [SNOMED CT concept]
- Product containing hydralazine (medicinal product) [SNOMED CT concept]
- hydrALAZINE [LOINC component]
- hydralazine [ATC Code]
- hydralazine [Substance BNPC]
- hydralazine [MeSH concept]
- hydralazine [SNOMED Notion]
- hydralazine [MeSH Descriptor]
Validated automatic mappings to BTNT
- hydralazine [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Hydralazine Hydrochloride [NCIt concept]
is_free_acid_or_base_form_of
- Hydralazine Hydrochloride [NCIt concept]

Keyword's position in hierarchy(ies) :

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