NCIt definition : A thienopyridine derivative with anticoagulant activity. Ticlopidine inhibits adenosine-diphosphate
(ADP) binding to its platelet receptor. This prevents ADP activation and inhibits
platelet expression of the glycoprotein (GP) IIb/IIIA receptors, binding of fibrinogen
to platelet glycoprotein GP IIb-IIIa and platelet-platelet interaction. This results
in increased bleeding time.;