" /> Sulbactam - CISMeF





Preferred Label : Sulbactam;

NCIt synonyms : (2S,5R)-3,3-Dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid 4,4-dioxide;

NCIt definition : A semi-synthetic beta-lactamase inhibitor. The beta-lactam ring of sulbactam irreversibly binds to beta-lactamase at or near its active site, thereby blocking enzyme activity and preventing metabolism of other beta-lactam antibiotics by the enzyme. Combining this agent with a beta-lactamase susceptible antibiotic, such as penicillins or a cephalosporin, to treat infections caused by beta-lactamase producing organisms, results in a decreased turnover rate of the beta-lactamase sensitive antibiotic and enhances its antibacterial activity.;

UNII : S4TF6I2330;

InChIKey : FKENQMMABCRJMK-RITPCOANSA-N;

CAS number : 68373-14-8;

Molecule name : CP 45899;

Chemical formula : C8H11NO5S;

ChEBI ID : CHEBI:9321;

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10/05/2025


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