Sulbactam Sodium

Preferred Label : Sulbactam Sodium;

NCIt synonyms : Sodium(2S,5R)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylate 4,4-Dioxide; Penicillanic Acid 1,1-dioxide, Sodium Salt; 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid, 3,3-dimethyl-7-oxo-, 4,4-dioxide, Sodium Salt,(2S-cis)-;

NCIt definition : The sodium salt form of sulbactam, a beta-lactam with weak antibacterial property. Sulbactam sodium contains a beta-lactam ring and irreversibly binds to beta-lactamase at or near its active site, thereby blocking enzyme activity and preventing metabolism of other beta-lactam antibiotics. Combining this agent with a beta-lactamase sensitive antibiotic such as penicillins and cephalosporins against penicillinase-producing and beta-lactamase-producing organisms, results in a decreased turnover rate of the sensitive antibiotic and enhances its antibacterial property.;

UNII : DKQ4T82YE6;

InChIKey : NKZMPZCWBSWAOX-IBTYICNHSA-M;

CAS number : 69388-84-7;

Chemical formula : C8H10NO5S.Na;

Details

Origin ID

C47732;

UMLS CUI

C0282355;

Automatic exact mappings (from CISMeF team)
- sulbactam [MeSH Descriptor]
Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Sulbactam Sodium [MeSH concept]
- Sulbactam sodium (product) [Inactive SNOMED CT concept]
- Sulbactam sodium (substance) [SNOMED CT concept]
- sodium (2s-cis)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 4,4-dioxide [Substance BNPC]
Validated automatic mappings to NTBT
- sulbactam [MeSH Descriptor]
- sulbactam [Substance BNPC]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_free_acid_or_base_form
- Sulbactam [NCIt concept]
is_salt_form_of
- Sulbactam [NCIt concept]

Keyword's position in hierarchy(ies) :

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