NCIt definition : An ethanolamine derivative with Class III antiarrhythmic and antihypertensive properties.
Sotalol is a nonselective beta-adrenergic receptor and potassium channel antagonist.
In the heart, this agent inhibits chronotropic and inotropic effects thereby slowing
the heart rate and decreasing myocardial contractility. This agent also reduces sinus
rate, slows conduction in the atria and in the atrioventricular (AV) node and increases
the functional refractory period of the AV node.;