Pramlintide - CISMeF

Preferred Label : Pramlintide;

NCIt synonyms : Triproamylin;

NCIt definition : A peptide analogue of human amylin with 3 proline substitutions at positions 25, 28 and 29, with antihyperglycemic activity. By mimicking amylin, pramlintide slows gastric emptying, inhibits digestive secretions (gastric acid, pancreatic enzymes, and bile), reduces glucagon secretion, and increases satiety; all of these actions are mediated mostly by glucose-sensitive areas in the brain stem. The overall result is a decrease in blood glucose levels. The use of pramlintide may cause an increased risk of insulin-induced hypoglycemia.;

UNII : D3FM8FA78T;

CAS number : 151126-32-8; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 151126-32-8 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Chemical formula : C171H267N51O53S2;

Details

Origin ID

C61901;

UMLS CUI

C0537551;

Automatic exact mappings (from CISMeF team)
- Pramlintide [ICD-11 Extension code]
- Pramlintide (substance) [SNOMED CT concept]
- Tripro-Amylin [MeSH concept]
Currated CISMeF NLP mapping
- Product containing pramlintide (medicinal product) [SNOMED CT concept]
- pramlintide [MeSH concept]
- pramlintide [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Hormone [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Pramlintide (substance) [SNOMED CT concept]
- Product containing pramlintide (medicinal product) [SNOMED CT concept]
- pramlintide [ATC Code]
- pramlintide [MeSH Supplementary Concept]
- pramlintide [MeSH concept]
Validated automatic mappings to BTNT
- pramlintide [ATC Code]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_salt_form
- Pramlintide Acetate [NCIt concept]
is_free_acid_or_base_form_of
- Pramlintide Acetate [NCIt concept]

Keyword's position in hierarchy(ies) :

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