NCIt definition : An aminoglycoside antibiotic derived from Streptomyces rimosus var. paromomycinus,
with amebicidal and antibacterial activity. Paromomycin binds specifically to the
RNA oligonucleotide at the A site of bacterial 30S ribosomes, thereby causing misreading
and premature termination of translation, thereby leading to inhibition of protein
synthesis followed by cell death.;