" /> Paromomycin Sulfate - CISMeF





Preferred Label : Paromomycin Sulfate;

NCIt synonyms : Aminosidine Sulfate; Humycin sulfate; D-Streptamine, O-2-amino-2-deoxy-alpha-D-glucopyranosyl-(1- 4)-O-(O-2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl-(1- 3)-beta-D-ribofuranosyl-(1- 5))-2-deoxy-, Sulfate(salt);

NCIt definition : The sulfate salt form of paromomycin, a structural derivative of neomycin, an aminoglycoside antibiotic with amebicidal and bactericidal effects against predominantly aerobic gram-negative bacteria. Paromomycin binds specifically to the RNA oligonucleotide at the A site of bacterial 30S ribosomes, thereby causing misreading and premature termination of translation of mRNA and inhibition of protein synthesis followed by cell death.;

UNII : 845NU6GJPS;

InChIKey : LJRDOKAZOAKLDU-UDXJMMFXSA-N;

CAS number : 1263-89-4;

Drug name : Humatin;

Chemical formula : C23H45N5O14.H2SO4;

NSC code : 227228;

ChEBI ID : CHEBI:7935;

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09/05/2025


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