Oxiconazole - CISMeF

Preferred Label : Oxiconazole;

NCIt definition : A broad spectrum imidazole derivative with antifungal activity. Although the exact mechanism of action has yet to be fully elucidated, oxiconazole, like other azole antifungals, most likely inhibits the cytochrome P450-dependent demethylation of lanosterol. This prevents the synthesis of ergosterol which is a crucial component of fungal cell membrane. By disrupting fungal cell membrane synthesis and integrity, oxiconazole alters fungal cell membrane permeability, promotes loss of essential intracellular components and eventually inhibits fungal cell growth.;

UNII : C668Q9I33J;

InChIKey : QRJJEGAJXVEBNE-HKOYGPOVSA-N;

CAS number : 64211-45-6;

Chemical formula : C18H13Cl4N3O;

Details

Origin ID

C61869;

UMLS CUI

C0069765;

Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Oxiconazole [ICD-11 Extension code]
- Oxiconazole (substance) [SNOMED CT concept]
- Product containing oxiconazole (medicinal product) [SNOMED CT concept]
- oxiconazole [ATC Code]
- oxiconazole [ATC Code]
- oxiconazole [MeSH concept]
- oxiconazole [SNOMED Notion]
- oxiconazole [MeSH Supplementary Concept]
Validated automatic mappings to BTNT
- oxiconazole [ATC Code]
- oxiconazole [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Oxiconazole Nitrate [NCIt concept]
is_free_acid_or_base_form_of
- Oxiconazole Nitrate [NCIt concept]

Keyword's position in hierarchy(ies) :

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