Midodrine - CISMeF

Preferred Label : Midodrine;

NCIt definition : A direct-acting prodrug and sympathomimetic agent with antihypotensive properties. Midodrine is converted to its active metabolite, desglymidodrine by deglycination reaction. Desglymidodrine selectively binds to and activates alpha-1-adrenergic receptors of the arteriolar and venous vasculature. This causes smooth muscle contraction and leads to an elevation of blood pressure. Desglymidodrine diffuses poorly across the blood-brain barrier, and is therefore not associated with effects on the central nervous system (CNS).;

UNII : 6YE7PBM15H;

InChIKey : PTKSEFOSCHHMPD-UHFFFAOYSA-N;

CAS number : 42794-76-3;

Chemical formula : C12H18N2O4;

ChEBI ID : CHEBI:6933;

Details

Origin ID

C61846;

UMLS CUI

C0026078;

Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Midodrine (substance) [SNOMED CT concept]
- Product containing midodrine (medicinal product) [SNOMED CT concept]
- midodrine [ATC Code]
- midodrine [Substance BNPC]
- midodrine [MeSH Descriptor]
- midodrine [MeSH concept]
Validated automatic mappings to BTNT
- midodrine [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Midodrine Hydrochloride [NCIt concept]
is_free_acid_or_base_form_of
- Midodrine Hydrochloride [NCIt concept]

Keyword's position in hierarchy(ies) :

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