" /> Midodrine - CISMeF





Preferred Label : Midodrine;

NCIt definition : A direct-acting prodrug and sympathomimetic agent with antihypotensive properties. Midodrine is converted to its active metabolite, desglymidodrine by deglycination reaction. Desglymidodrine selectively binds to and activates alpha-1-adrenergic receptors of the arteriolar and venous vasculature. This causes smooth muscle contraction and leads to an elevation of blood pressure. Desglymidodrine diffuses poorly across the blood-brain barrier, and is therefore not associated with effects on the central nervous system (CNS).;

UNII : 6YE7PBM15H;

InChIKey : PTKSEFOSCHHMPD-UHFFFAOYSA-N;

CAS number : 42794-76-3;

Chemical formula : C12H18N2O4;

ChEBI ID : CHEBI:6933;

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28/07/2025


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