NCIt definition : A semisynthetic, narrow spectrum beta-lactamase-resistant penicillin antibiotic with
bactericidal and beta-lactamase resistant activity. Methicillin binds to specific
penicillin-binding proteins (BPBs) on the bacterial cell wall, thereby preventing
the cross-linkage of peptidoglycans, which are critical components of the bacterial
cell wall. This leads to an interruption of the bacterial cell wall and causes bacterial
lysis.;