Preferred Label : Methicillin Sodium;
NCIt synonyms : Celbenin; Staphcillin; 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid, 6-((2,6-dimethoxybenzoyl)amino)-3,3-dimethyl-7-oxo-,
Monosodium Salt, Monohydrate,(2S-(2alpha,5alpha,6beta))-;
NCIt definition : The sodium salt form of methicillin, a semisynthetic beta-lactam penicillin antibiotic
with beta-lactamase resistant activity. Methicillin sodium is bactericidal and binds
to specific penicillin-binding proteins on the bacterium and inhibits the transpeptidation
enzyme, thereby preventing the cross-linking of peptidoglycans. This leads to an interruption
of the bacterial cell wall and causes bacterial lysis. Methicillin sodium is active
against beta-lactamase producing staphylococci.;
UNII : AO9YF4MN30;
InChIKey : NRZPASQBOYNGHR-HWROMZCQSA-M;
CAS number : 7246-14-2;
Chemical formula : C17H19N2O6S.Na.H2O;
ChEBI ID : CHEBI:34836;
Origin ID : C47611;
UMLS CUI : C0887175;
Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- See also inter- (CISMeF)
- Semantic type(s)
- UMLS correspondences (same concept)
- concept_is_in_subset
- has_free_acid_or_base_form
- is_salt_form_of
