NCIt definition : A synthetic mast cell stabilizing compound with anti-inflammatory activity. Lodoxamide
appears to inhibit the antigen-stimulated calcium transport across the mast cell membrane,
thereby inhibiting mast cell degranulation and the release of histamine, leukotrienes,
and other substances that cause hypersensitivity reactions. Lodoxamide also inhibits
eosinophil chemotaxis. When applied topically to the eye, this drug prevents the symptoms
associated with keratitis or conjunctivitis.;