NCIt definition : A benzyl alcohol derivative with vasodilator activity. The mechanism of action of
isoxsuprine hydrochloride is controversial, because isoxsuprine has beta-adrenergic
activities that could not be offset by beta-adrenergic blockers. Although stimulation
of the beta adrenergic receptor increases blood flow to produce vasodilatation, this
agent may also have direct effects on the contractility of smooth muscle. Additionally,
isoxsuprine causes relaxation of uterine smooth muscle and may also produce positive
inotropic and chronotropic effects on the myocardium.;