NCIt definition : The hydrochloride salt of isoxsuprine, a benzyl alcohol derivative with vasodilator
activity. The mechanism of action of isoxsuprine hydrochloride is controversial because
this drug has beta-adrenergic agonist activities that are not reversed by beta-adrenergic
blockers. Although stimulation of the beta adrenergic receptor increases blood flow
to produce vasodilatation, this drug may also have direct effects on the contractility
of smooth muscle. Isoxsuprine hydrochloride also causes relaxation of uterine smooth
muscle and may also produce positive inotropic and chronotropic effects on the myocardium.;