" /> Gemifloxacin - CISMeF





Preferred Label : Gemifloxacin;

NCIt definition : A fluoroquinolone antibiotic with antimicrobial property. Gemifloxacin enters bacterial cells by diffusion through integral membrane porin pathway before targeting both DNA gyrase and topoisomerase IV, two enzymes critical for DNA replication and repair. This agent binds to the DNA/DNA-gyrase complex and inhibits the A subunits of the enzyme thereby preventing the bacterial chromosome from rejoining. This interferes with DNA replication and repair processes as well as transcription, and ultimately leads to bacterial cell death. Gemifloxacin targets at both Gram-positive, -negative and atypical human pathogens.;

UNII : OKR68Y0E4T;

InChIKey : ZRCVYEYHRGVLOC-HYARGMPZSA-N;

CAS number : 204519-64-2; 175463-14-6; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 204519-64-2 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 175463-14-6 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Chemical formula : C18H20FN5O4;

ChEBI ID : CHEBI:101853;

Details


Keyword's position in hierarchy(ies) : arborescence

You can consult :


Nous contacter.
02/06/2024


[Home] [Top]

© Rouen University Hospital. Any partial or total use of this material must mention the source.