Econazole - CISMeF

Preferred Label : Econazole;

NCIt definition : An imidazole with antifungal property. Econazole compromises the integrity of fungal cell wall through inhibiting 14-alpha demethylase, which catalyzes conversion of lanosterol to ergosterol, an essential component of the fungal cell wall. As a result, this agent increases cellular permeability thereby resulting in leakage of cellular contents. Furthermore, econazole has also been implicated to inhibit endogenous respiration, interact with membrane phospholipids, inhibit purine uptake, and impair triglyceride and/or phospholipid biosynthesis.;

UNII : 6Z1Y2V4A7M;

InChIKey : LEZWWPYKPKIXLL-UHFFFAOYSA-N;

CAS number : 27220-47-9;

Chemical formula : C18H15Cl3N2O;

ChEBI ID : CHEBI:4754;

Details

Origin ID

C61740;

UMLS CUI

C0013547;

Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Econazole [ICD-11 Extension code]
- Econazole [LOINC component]
- Econazole (substance) [SNOMED CT concept]
- Product containing econazole (medicinal product) [SNOMED CT concept]
- econazole [ATC Code]
- econazole [ATC Code]
- econazole [Substance BNPC]
- econazole [MeSH concept]
- econazole [MeSH Descriptor]
- econazole [SNOMED Notion]
Validated automatic mappings to BTNT
- econazole [ATC Code]
- econazole [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Econazole Nitrate [NCIt concept]
is_free_acid_or_base_form_of
- Econazole Nitrate [NCIt concept]

Keyword's position in hierarchy(ies) :

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