Preferred Label : Diphenhydramine;
NCIt synonyms : Rigidyl; O-Benzhydryldimethylaminoethanol; 2-(Diphenylmethoxy)-N,N-dimethylethylamine; Probedryl;
NCIt definition : A first generation antihistamine and ethanolamine with sedative and anti-allergic
properties. Diphenhydramine competitively inhibits the histamine-1 (H1) receptor,
thereby alleviating the symptoms caused by endogenous histamine on bronchial, capillary
and gastrointestinal smooth muscles. This prevents histamine-induced bronchoconstriction,
vasodilation, increased capillary permeability, and GI smooth muscle spasms.;
Alternative definition : NCI-GLOSS: A drug used to treat allergies and relieve cough and itching caused by
insect bites, sunburn, and poison oak or ivy. It is also used to treat mild Parkinson
disease, to prevent and treat motion sickness, to relieve cough and cold symptoms,
and as a sleep aid. It is a type of antihistamine.;
UNII : 8GTS82S83M;
InChIKey : ZZVUWRFHKOJYTH-UHFFFAOYSA-N;
CAS number : 58-73-1;
Drug name : Syntedril;
Molecule name : PM 255; FAR 90X2; S51;
Chemical formula : C17H21NO;
ChEBI ID : CHEBI:4636;
Codes from synonyms : CDR0000449930; 01519; 162;
Origin ID : C61728;
UMLS CUI : C0012522;
See also inter- (CISMeF)
Semantic type(s)
UMLS correspondences (same concept)
Validated automatic mappings to BTNT
concept_is_in_subset
has_salt_form
is_free_acid_or_base_form_of