Diphenhydramine Hydrochloride

Preferred Label : Diphenhydramine Hydrochloride;

NCIt related terms : Eldadryl; Bendylate; Benadryl; SK-Diphenhydramine; Diphenhydramine.HCl;

NCIt definition : The hydrochloride salt form of diphenhydramine, an ethanolamine and first-generation histamine antagonist with anti-allergic activity. Diphenhydramine hydrochloride competitively blocks H1receptors, thereby preventing the actions of histamine on bronchial smooth muscle, capillaries, and gastrointestinal (GI) smooth muscle. This prevents histamine-induced bronchoconstriction, vasodilation, increased capillary permeability, and GI smooth muscle spasms.;

UNII : TC2D6JAD40;

InChIKey : PCHPORCSPXIHLZ-UHFFFAOYSA-N;

CAS number : 147-24-0;

Drug name : Eldadryl; Bendylate; SK-Diphenhydramine; Benadryl;

Chemical formula : C17H21NO.HCl;

NSC code : 33299;

ChEBI ID : CHEBI:4637;

Codes from synonyms : 1520; NSC0033299;

Details

Origin ID

C300;

UMLS CUI

C0004963;

Automatic exact mappings (from CISMeF team)
- diphenhydramine [MeSH Descriptor]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
Validated automatic mappings to NTBT
- diphenhydramine [MeSH Descriptor]
- diphenhydramine [Substance BNPC]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_free_acid_or_base_form
- Diphenhydramine [NCIt concept]
is_salt_form_of
- Diphenhydramine [NCIt concept]

Keyword's position in hierarchy(ies) :

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