Preferred Label : Dexchlorpheniramine;
NCIt synonyms : D-Chlorpheniramine; Chlo-amine; 2-Pyridinepropanamine, gamma-(4-chlorophenyl)-N,N-dimethyl-, (S)-; D-2-(p-Chloro-alpha-(2-dimethylaminoethyl)benzyl)pyridine;
NCIt definition : An alkylamine, and first-generation histamine antagonist with anti-allergic activity.
Dexchlorpheniramine competitively blocks H1 receptors, thereby preventing the actions
of histamine on bronchial smooth muscle, capillaries and gastrointestinal (GI) smooth
muscle. The antagonistic action of this agent blocks the activities of endogenous
histamine, thereby preventing histamine-induced bronchoconstriction, vasodilation,
increased capillary permeability, and GI smooth muscle spasms.;
UNII : 3Q9Q0B929N;
InChIKey : SOYKEARSMXGVTM-HNNXBMFYSA-N;
CAS number : 25523-97-1;
Chemical formula : C16H19ClN2;
ChEBI ID : CHEBI:4464;
Codes from synonyms : 157;
Origin ID : C61707;
UMLS CUI : C0057606;
Automatic exact mappings (from CISMeF team)
- Semantic type(s)
- UMLS correspondences (same concept)
- Validated automatic mappings to BTNT
- concept_is_in_subset
- has_salt_form
- is_free_acid_or_base_form_of
