Dexchlorpheniramine Maleate

Preferred Label : Dexchlorpheniramine Maleate;

NCIt synonyms : (gamma-(4-Chlorophenyl)-pyridine-2-propyl)(dimethyl)ammonium hydrogen(Z)-maleate; ( )-2-(p-Chloro-alpha-(2-(dimethylamino)ethyl)benzyl)pyridine Maleate(1:1); d-Chlorpheniramine Maleate; S-( )-Chlorpheniramine Maleate;

NCIt definition : The maleate salt form of dexchlorpheniramine, an alkylamine, and first-generation histamine antagonist with anti-allergic activity. Dexchlorpheniramine maleate competitively blocks H1 receptors, thereby preventing the actions of histamine on bronchial smooth muscle, capillaries and gastrointestinal (GI) smooth muscle. This prevents histamine-induced bronchoconstriction, vasodilation, increased capillary permeability, and GI smooth muscle spasms.;

UNII : B10YD955QW;

InChIKey : DBAKFASWICGISY-DASCVMRKSA-N;

CAS number : 2438-32-6;

Drug name : Mylaramine; Polaramine;

Chemical formula : C16H19ClN2.C4H4O4;

Details

Origin ID

C47478;

UMLS CUI

C0137440;

Automatic exact mappings (from CISMeF team)
- chlorpheniramine [MeSH Descriptor]
- dexchlorpheniramine [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Dexchlorpheniramine maleate (substance) [SNOMED CT concept]
- dexchlorpheniramine maleate [International Nonproprietary Name]
- dexchlorpheniramine maleate [Substance BNPC]
- dexchlorpheniramine maleate [MeSH concept]
- dexchlorpheniramine maleate [SNOMED Notion]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_free_acid_or_base_form
- Dexchlorpheniramine [NCIt concept]
is_salt_form_of
- Dexchlorpheniramine [NCIt concept]

Keyword's position in hierarchy(ies) :

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