NCIt definition : A recombinant ovine corticotropin-releasing hormone (CRH), a 41 amino acids peptide
similar to human CRH, used as a diagnostic agent. Corticorelin ovine is a potent stimulator
of adrenocorticotropic hormone (ACTH), secreted from the anterior pituitary gland.
In turn, ACTH stimulates cortisol production from the adrenal cortex and is regulated
by a negative feedback mechanism. Corticorelin ovine triflutate is used as a diagnostic
tool in differentiating pituitary and ectopic production of ACTH.;