NCIt definition : A trifluoroacetate salt of ovine corticotropin-releasing hormone (CRH), a 41 amino
acids peptide similar to human CRH, used as a diagnostic agent. Corticorelin ovine
triflutate is a potent stimulator of adrenocorticotropic hormone (ACTH), secreted
from the anterior pituitary gland. In turn, ACTH stimulates cortisol production from
the adrenal cortex and is regulated by a negative feedback mechanism. Corticorelin
ovine triflutate is used as a diagnostic tool in differentiating pituitary and ectopic
production of ACTH.;