Ciclopirox - CISMeF

Preferred Label : Ciclopirox;

NCIt definition : A synthetic, broad-spectrum antifungal agent with additional antibacterial and anti-inflammatory activities. Ciclopirox exerts its action by binding to and chelating trivalent cations, such as Fe3 and Al3 , thereby inhibiting the availability of essential co-factors for enzymes. This may lead to a loss of activity of enzymes that are essential for cellular metabolism, organization of cell wall structure and other crucial cell functions. In addition, ciclopirox exerts its anti-inflammatory activity by inhibiting 5-lipoxygenase and cyclooxygenase (COX).;

UNII : 19W019ZDRJ;

InChIKey : SCKYRAXSEDYPSA-UHFFFAOYSA-N;

CAS number : 29342-05-0;

Chemical formula : C12H17NO2;

ChEBI ID : CHEBI:453011;

Details

Origin ID

C61677;

UMLS CUI

C0055711;

Automatic exact mappings (from CISMeF team)
- Ciclopirox (olamine) [ICD-11 Extension code]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Ciclopirox [MeSH Descriptor]
- Ciclopirox (substance) [SNOMED CT concept]
- Product containing ciclopirox (medicinal product) [SNOMED CT concept]
- ciclopirox [ATC Code]
- ciclopirox [ATC Code]
- ciclopirox [Substance BNPC]
- ciclopirox [MeSH concept]
- ciclopirox [SNOMED Notion]
Validated automatic mappings to BTNT
- ciclopirox [ATC Code]
- ciclopirox [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Ciclopirox Olamine [NCIt concept]
is_free_acid_or_base_form_of
- Ciclopirox Olamine [NCIt concept]

Keyword's position in hierarchy(ies) :

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