Preferred Label : Alpha-Lipoic Acid;
NCIt synonyms : Lipoic Acid; 6,8-Thioctic Acid; 5-(1,2-Dithiolan-3-yl)pentanoic Acid; Thioctate;
NCIt related terms : Thioctic Acid; ALPHA LIPOIC ACID;
NCIt definition : A naturally occurring micronutrient, synthesized in small amounts by plants and animals
(including humans), with antioxidant and potential chemopreventive activities. Alpha-lipoic
acid acts as a free radical scavenger and assists in repairing oxidative damage and
regenerates endogenous antioxidants, including vitamins C and E and glutathione. This
agent also promotes glutathione synthesis. In addition, alpha-lipoic acid exerts metal
chelating capacities and functions as a cofactor in various mitochondrial enzyme complexes
involved in the decarboxylation of alpha-keto acids.;
Alternative definition : NCI-GLOSS: A substance that is being studied for its ability to protect normal cells
from the side effects of chemotherapy and prevent peripheral neuropathy (numbness,
tingling, burning, and weakness in the hands or feet). Alpha-lipoic acid is made by
the body and can be found in foods such as organ meats, spinach, broccoli, peas, brussel
sprouts, and rice bran. It can also be made in the laboratory. Alpha-lipoic acid is
a type of antioxidant and chemoprotective agent.;
UNII : 73Y7P0K73Y;
InChIKey : AGBQKNBQESQNJD-UHFFFAOYSA-N;
CAS number : 1077-28-7;
Chemical formula : C8H14O2S2;
ChEBI ID : CHEBI:16494;
Codes from synonyms : CDR0000443026; 03352;
Origin ID : C61595;
UMLS CUI : C0023791;
Automatic exact mappings (from CISMeF team)
Currated CISMeF NLP mapping
Semantic type(s)
UMLS correspondences (same concept)
concept_is_in_subset
https://www.cochrane.org/fr/CD012967/NEUROMUSC_lacide-alpha-lipoique-un-antioxydant-naturel-est-il-preferable-labsence-de-traitement-ou-un
2024
United Kingdom
review of literature
french abstract
thioctic acid
artificial
Illinois
Alpha-Lipoic Acid
Israel
CDISC SDTM Diabetes Therapy Terminology
No Treatment due to Device Malfunction
lesion, nos
Biological Son
Alpha
Alpha
wounds and injuries
Is Preferred
Nerve Damage
No Treatment for Diabetes
persons
Interleukin
Prothrombin Measurement
Diabetes Therapy
acid, nos
disease
diabetes mellitus
antioxidants
What Month is it
People
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